Sigma-Aldrich develops life science products in the form of biochemical and reagents. The antibody products include flow cytometry antibodies. Antigens, lgY antibodies, antibodies for proximity ligation assays, and antibody kits. The primary antibodies for flow cytometry that Sigma-Aldrich develops are monoclonal. The antibodies are available in two forms: conjugated or purified. The company also produces other reagents such as blocking agents, controls, and purified immunoglobulins.
Sigma-Aldrich also provides antibodies in whole molecule form and as fragments known as F(ab)2. In addition to whole antiserum and F(ab)2antibodies, Sigma-Alrich produces numerous types other common types of antibodies such as fractionated antiserum, IgG fraction of antiserum, affinity isolate antibody (AIA), ascites fluid, tissue culture supernatant, and purified immunoglobulin.
The primary antibodies that are developed by Sigma-Aldrich have several biological applications, which include molecular biology, neurobiology, and cell biology. Secondary antibodies have targets that serves as conjugations for FITC, peroxidase, biotin, and alkaline phosphatase.
The Proximity Ligation Assay (PLA) antibodies that are generated by Sigma-Aldrich and Bethyly Laboratories are produced by combining reagents that have been pre-qualified with Duolink technology. This collection of antibodies are specific for PLA research projects, and are developed to work with either primary or secondary conjugate detection. The PLA antibodies are available individually and in indirect detection and direct detection kits.
Sigma-Alrich offers Prestige Antibodies ®, which are generated by an initiative called Human Protein Atlas (HPA). Sigma-Alrich partners with the Atlas Antibodies company to produce these antibodies. The categories of Prestige Antibodies include monoclonal and polyclonal antibodies and antigens. These antibodies are produced through a workflow that includes antibody generation, application specific validation, and protein expression profiling. These antibodies have several applications, which include immunofluorescence, neuroscience, breast cancer research, and Western blotting. In regards to Western blotting, Prestige Antibodies support more than 700 of their images.
The Sigma-Alrich website provides researchers several tools to assist them with their research analysis projects. The analytical standards explorer is a search tool that allows researchers to find specific certification documents. Another The Pressure-Temperature Nomograph enables researchers to gauge boiling point at several pressure levels. The Nomograph has interactive controls that streamline the calculation process and help to make distillation more efficient. The unit converter is a basic tool for converting measurements such as volume, length, flow rate, density, torque, pressure, and mass. The normality & molarity calculator is designed to generate steps for using a concentrated base or acid solution to prepare the same type of solutions but with a specific molarity or normality. Sigma-Alrich offers similar calculators to generate instructions for mass molarity and solution dilution.
The structure search and JS Draw tool are also available for researchers. The structure search tool is used to search the Sigma-Alrich catalog by structure. The JS Draw tool is a product for drawing chemicals.
The antibody explorer search is a tool for searching the Sigma-Alrich catalog for antibodies. The company catalog includes polyclonal and monoclonal primary antibodies as well as secondary antibodies. The purpose of the antibody explorer search tool is to allow researchers to search by antigen, gene, species, application, label, and more.
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My other passions include grilling, wine tasting, and real food. To be honest, my biggest passion is flow cytometry, which is something that Carol and I share. My personal mission is to make flow cytometry education accessible, relevant, and fun. I’ve had a long history in the field starting all the way back in graduate school.